Search Criteria: Bone and Muscle Studies;
Amniotic Fluid Epidural Injection for People with Low Back and Hip Pain caused by pressure on the Spinal Cord
(IRB#: IRB_00131761)
Lumbosacral radicular pain is in the low back and hip caused by pressure on the spinal cord. The human amniotic fluid epidural injection is a new way to reduce this pain. Corticosteroid dexamethasone is the standard of care to improve symptoms. Research is needed to learn which is more effective at helping people with the condition. The information we learn will aid future patients.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Barriers to Low Back Pain Healthcare for People who are Underserved
(IRB#: IRB_00156672)
Low back pain can require imaging (taking a picture) and other medical needs of the lumbar, (lower part of the back). People may have issues attending appointments for their lower back pain. These include language and translation services and lack of health insurance. The study wants to learn how to better help people attend their appointments for low back pain. Being in the study requires completing a survey. The questions may ask about needing an interpreter, health insurance, childcare, or transportation. People who need health insurance or an interpreter will be given help to attend the appointment. The study team will gather data to learn how to better help participants attend doctor appointments. Information collected will not identify the persons name, address, or phone number.
- All genders
- Over 18 years old
- Volunteers with special conditions
- From Home
- Unpaid
Cervical Medial Branch Radiofrequency Ablation (CMBRFA) compared to Trident Multi-tined Cannula for People with Cervical Facet Pain
(IRB#: IRB_00143800)
Cervical facet pain is an arthritis-like joint pain that can be chronic and occur in the back and neck of the spine. Cervical medial branch radiofrequency ablation (CMBRFA) is an effective treatment for this health issue. Trident Multi-tined Cannula is also a way to help people with cervical pain. Research is needed to learn the characteristics and effectiveness of Trident Multi-tined Cannula compared to CMBRFA. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Improve Technology to Rehabilitate People with Non-Mobility and Mobility Impairment
(IRB#: IRB_00160259)
Smart Technology may be used to help rehabilitate people from injuries. Technology can measure a persons movements such as how they walk. There is a new technology that might reduce the cost and amount of time required to recover from an injury. Research is needed to see if the new technology improves rehabilitation for adults with non-mobility and mobility.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Laser Evoked Potentials (LEP) in Patients with Low Back Pain and Healthy Volunteers
(IRB#: IRB_00158608)
People with low back pain may need testing for diagnoses and treatment evaluations. Research is needed to assess if more quantitative measures such as laser evoked potential (LEP) and quantitative sensory testing can be used to tease out differences in patients with low back pain problems and better determine the treatment outcomes. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Metformin and Muscle Health Recovery
(IRB#: IRB_00175808)
Times of physical inactivity such as illness, recovery from surgery, or injury in older adults may harm muscle health. Research is needed to learn of ways to improve the muscle response to physical activity and recovery. We will determine if metformin, a diabetes drug, improves muscle recovery during physical inactivity. The information we gain may allow us to better design ways to help muscle health when older adults or those who are overweight become physically inactive and have rehabilitation.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
MODEL Study: SB-01, A Study Drug for People with Degenerative Disc Disease in the Lower Back of the Spine
(IRB#: IRB_00154298)
Degenerative disc disease can occur in the lower back of a persons spine. This disease can cause severe back pain and cause disability. SB-01 is a study drug to help people with this disease. Research is needed to study the safety and effectiveness of this drug. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Physical Inactivity and Muscle Health Recovery
(IRB#: IRB_00130232)
Times of physical inactivity such as illness, recovery from surgery, or injury in older adults and those who are overweight may harm muscle health. Research is needed to learn how different markers such as hormones and proteins in the blood and muscle respond to physical activity and recovery. The information we gain may allow us to better design ways to help muscle health when older adults or those who are overweight become physically inactive and have rehabilitation.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Platelet-Rich Plasma for Labrum Tears of the Hip
(IRB#: IRB_00173470)
Platelets are small cells found in the blood that help form clots and stop bleeding. Platelet-rich plasma is blood that contains more platelets than normal and can be given to help people with pain. Tears of the Labrum to the hip (the cartilage "suction cup" that holds the ball to the socket of the hip) cause hip pain. The study wants to see if a portion of the patient's blood, the platelets, will help relieve hip pain and function. Participation requires completing surveys by email, text message, in person, and/or by telephone. Medical tests will also be done to track the health of participants. Participants will receive a gift card for the time spent in the study.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Radiofrequency Ablation for People with Sacroiliac Joint Pain
(IRB#: IRB_00150067)
Radiofrequency ablation (RFA) is a way to help people with lower back pain. The pain is caused by swelling or arthritis in the sacroiliac joints. This is where the lower spine and pelvis connect in a persons back. Research is needed to compare 2 types of RFA electrodes (an object that allows electricity to enter and leave a persons body safely). We want to learn which electrode works best in reducing joint pain. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Shoulder RFA for the Treatment of Non-Surgical Shoulder Pain
(IRB#: IRB_00159158)
Shoulder pain can cause chronic health issues and costs. Currently, there are not many options to help people with this condition. Research is needed to learn the safety and effectiveness of shoulder radiofrequency ablation (SRFA) in patients with specific shoulder pain. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
SL-1002 Injection Treatment for People with Knee Pain and Osteoarthritis (OA)
(IRB#: IRB_00154817)
Osteoarthritis (OA) is a disease that causes joint pain. This can occur in the knee. The Corticosteroid dexamethasone injection is used now to help people with OA knee pain. The human amniotic fluid epidural injection is a new way to treat this pain. Research is needed to learn the safety and effectiveness of the new injection and see which injection is better at improving symptoms. The information we learn will aid future patients.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Testing Meditation Group Therapy for Chronic Low Back Pain
(IRB#: IRB_00133405)
This study is comparing therapy to treat people with chronic (constant) low back pain. The study is testing usual care for people using opioids (medication to treat people's pain) versus usual care for people using opioids with meditation-based therapy (mental training involving focusing the mind to cope with pain, stress, and emotions). The study wants to better understand how well the usual care with meditation-based therapy works and if it creates changes in brain activity over time. People in the study will be randomly chosen to be treated with or without meditation therapy. Being in the study lasts about 6 months. Medical tests will be done during the study to learn and track the health of participants. People with be paid for participation.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
The Intracept Procedure for People with Low Back Pain
(IRB#: IRB_00130205)
The Intracept procedure is given by a patients specific doctor for low back pain. The procedure is approved by the (Food and Drug Administration) FDA. Research is needed to learn more about how well and safe it is at helping a persons lower back pain. The information we learn will aid future patients.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
The SPRINT® System a Nerve Stimulator for People with Head Pain
(IRB#: IRB_00159617)
The SPRINT® system can block nerves that send pain signals to the brain. Research is needed to learn how safe the SPRINT® system stimulator is and how well it helps people with head pain. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid