Study Details
Testing the Drug IMVT-1402 in Adults with Graves Disease
(IRB#: IRB_00186900)
Graves' disease is an immune system disorder that impacts the thyroid, causing health issues. This study will test a drug called IMVT-1402 to treat people with this disease. The study wants to see if the drug will help people with the disease and is safe. People in the study will be randomly chosen to be treated with IMVT-1402 or a placebo. The placebo looks like the study drug but does not have the medication. Being in the study requires attending in-person visits at the study clinic, home visits, and telephone calls over about 52 weeks. Medical tests will be done to track the health of participants.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Who can participate?
Gender: All genders
Age: Over 18 years old
Volunteers: Volunteers with special conditions
Location: In Person
Inclusion Criteria
- Ages 18 to 75 years old
- Diagnosis of Graves' disease
- Must use specific birth control during the study and for 90 days after participation
- Able to attend in-person visits at the study clinic
Exclusion Criteria
- Any medical condition that impacts full study participation
- Specific body mass
- Active or history of cancer 5 years before participation
- History of serious allergies
- Blood drawn with the removal of a specific amount of blood 30 days prior to study participation
Will I be paid for my time?
Yes
IRB#: IRB_00186900
PI: Vishnu Sundaresh
Department: INTERNAL MEDICINE
Approval Date: 2025-06-25 06:00:00
Specialties: Endocrinology & Metabolism
I am Interested