Study Details
Testing the Drug Finerenone for Chronic Kidney Disease and Proteinuria
(IRB#: IRB_00169672)
Chronic Kidney Disease is when kidneys are damaged and cannot filter blood in the body. This can cause hypertension (high blood pressure), increase the body's release of urinary protein (proteinuria), and decline in renal (kidney) function. This study will test a drug called BAY 94-8862 (finerenone) to treat Chronic Kidney Disease and proteinuria. The study wants to see if the drug will help people with this is safe. People in this study will be randomly chosen to be treated with finerenone or a placebo. The drug and placebo are taken as a swallowed pill or liquid. A placebo looks like a drug but does not have the medication. Being in the study requires up to 10 study visits over 10 months. Study visits are held in person at the study clinic or a combination of in-person and using a video call or phone call. Medical tests will be done during the study to track the health of participants.
- All genders
- All Ages
- Volunteers with special conditions
- In Person
- Paid
Who can participate?
Gender: All genders
Age: All Ages
Volunteers: Volunteers with special conditions
Location: In Person
Inclusion Criteria
- Ages 6 months to 17 years old at the beginning of the study
- Diagnosis of Chronic Kidney Disease
- Use birth control if appropriate
- Able to attend in-person visits at a study clinic or a combination of in-person and using a video call or phone call
Exclusion Criteria
- Certain types of surgery that impact kidney function
- Hypertension (high blood pressure)
- Nephrotic Syndrome (kidneys produce too much protein in the urine) diagnosis 6 months before participation
- Scheduled kidney transplant during the study time
- Severe kidney injury 6 months before participation
Will I be paid for my time?
Yes
IRB#: IRB_00169672
PI: Raoul Nelson
Department: PEDIATRICS
Approval Date: 2024-06-19 06:00:00
Specialties: Pediatric Nephrology