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Study Details

Transcranial Magnetic Stimulation (TMS) for People with Depression in Multiple Sclerosis (MS)

(IRB#: IRB_00164631)

Multiple sclerosis (MS) is a disease that damages nerve cells in the brain and spinal cord. This can affect a persons physical and mental health. Depression, or major depressive disorder, is common in people with MS and often has a serious impact on quality of life. Depression can be difficult to treat with medications in MS. Transcranial magnetic stimulation (TMS) is a safe and approved treatment for medication in people with depression. Little is known about TMS for people with MS. This study wants to better understand the safety and effectiveness of TMS treatment for depression in MS. Participants will receive standard outpatient TMS treatment for depression. This includes in-person, phone, and online Zoom visits to complete surveys and track the health of participants.


  • All genders
  • Over 18 years old
  • Volunteers with special conditions
  •   In Person
  • Paid

Who can participate?

 Gender: All genders

  Age: Over 18 years old

  Volunteers: Volunteers with special conditions

   Location: In Person

Inclusion Criteria

  • Participants ages 18 to 75 years old diagnosed with multiple sclerosis (any subtype)
  • Currently diagnosed with major depressive disorder (MDD)
  • Eligible for TMS treatment for depression

Exclusion Criteria

  • Recent MS relapse or steroid use (within 3 months)
  • History of seizure, brain tumor, or stroke
  • History of bipolar disorder or psychosis
  • Currently or planning to become pregnant

Will I be paid for my time?


For more information contact:

Kathleen Shangraw


IRB#: IRB_00164631

PI: Kathleen Shangraw


Approval Date: 2024-01-03 07:00:00

Study Categories: Brain Health Studies, Mental Health and Well-being Studies

Specialties: Psychiatry

Last Updated: 6/8/23