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Study Details

Stem Cell Transplants and Disease Prevention for Children with ALL, AML, or MDS

(IRB#: IRB_00153852)

Acute lymphocytic leukemia (ALL) is a type of blood and bone marrow cancer. Acute myeloid leukemia (AML) is a type of blood cell and bone marrow cancer caused by too many undeveloped white blood cells. Myelodysplastic Syndromes (MDS) are a rare group of bone marrow disorders, known as blood cancer. We want to learn if patients receiving stem cell transplants from donors of any type (related, unrelated, cord, or haploidentical) with specific characteristics (different genetic make-up known as polymorphisms) will have better results than those with different transplants. We want to see if fewer diseases such as Graft v Host Disease (GvHD) and other disorders occur. The information we gain may aid future patients.


  • All genders
  • All Ages
  • Volunteers with special conditions
  •   In Person
  • Unpaid

Who can participate?

 Gender: All genders

  Age: All Ages

  Volunteers: Volunteers with special conditions

   Location: In Person

Inclusion Criteria

  • < 25 years for receiving transplants
  • 4 months and older for donors
  • Diagnosis of ALL, AML, MDS
  • High risk with first or second remission of ALL, AML, MDA
  • In-person at the University of Utah

Exclusion Criteria

  • Pregnant
  • Diagnosis of HIV
  • Active CNS (central nervous system) ALL
  • Diagnosed genetic disorder(s)

Will I be paid for my time?


For more information contact:

Karely Mann


IRB#: IRB_00153852

PI: Michael Pulsipher


Approval Date: 2023-04-05 06:00:00

Specialties: Pediatric Hematology & Oncology

Last Updated: 6/8/23