Study Details
Brain Stimulation for People with Treatment-Resistant Depression
(IRB#: IRB_00148802)
This study will test a new, non-invasive low risk method of brain stimulation for people with treatment-resistant depression. This study wants to test how an ultrasound will be used to reach a specific area of the brain and the immediate effects on a person's mood. The study wants to see if the ultrasound brain stimulation helps people with treatment-resistant depression. People in the study will complete surveys, experience brain stimulations, and magnetic resonance imaging (MRI) to scan the brain. Being in the study requires attending 10 visits to the study clinic over about 2 months, including visits with MRI scans.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Who can participate?
Gender: All genders
Age: Over 18 years old
Volunteers: Volunteers with special conditions
Location: In Person
Inclusion Criteria
- At least 2 failed attempts of anti-depressant medication and/or psychotherapy with at least one attempt during the current depressive state
- Willingness to not change medication regimen and psychotherapy schedule during the study participation.
- Currently receive care from a licensed psychiatrist or other mental health provider, or licensed addiction medicine specialist
- Provide verified contact information of at least 2 persons 22 years or older who live within 60 minutes from the participants home
- Able to attend in person visits at the study clinic including MRI scans
Exclusion Criteria
- History of serious brain injury or other neurological disorder such as concussion with loss of consciousness, epilepsy, traumatic brain injury
- Implanted device in the head or neck and MRI intolerance or fear of small spaces
- Brain stimulation treatment such as Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), or Vagus Nerve Stimulation (VNS) one month before participation
- History of a serious suicide attempt (lifetime), defined as a self-injurious act with intent to die that required medical intervention and was associated with high lethality or significant suicidal intent
- History of diagnosis of OCD, bipolar disorder, schizophrenia, neurocognitive disorder, severe personality disorder, substance use disorder
Will I be paid for my time?
Yes
IRB#: IRB_00148802
PI: Brian Mickey
Department: PSYCHIATRY
Approval Date: 2022-01-12 07:00:00
Study Categories: Mental Health and Well-being Studies
Specialties: Psychiatry
I am Interested