Study Details
Long-term study of foot and ankle anatomy in children and teens with Charcot-Marie-Tooth Disease
(IRB#: IRB_00195630)
CharcotMarieTooth (CMT) disease can affect how the feet and ankles grow and move. This study looks at how the bones and muscles in the feet and ankles change over time in children and teens with CMT. What we learn may help improve future treatments. The study includes three visits over two years. Children and teens with and without CMT will have medical imaging to take pictures of their feet and ankles. Those with CMT will also have genetic testing and simple tests of muscle strength, hand use, and walking. The movement tests will be repeated after one year and after two years.
- All genders
- Over 7 years old
- Healthy Volunteers
- In Person
- Paid
Who can participate?
Gender: All genders
Age: Over 7 years old
Volunteers: Healthy Volunteers
Location: In Person
Inclusion Criteria
- Age 7 to 18
- Participants diagnosed with CMT --OR-- Participants without CMT and no family history of neuromuscular (nerve and muscle) disease
- Able to walk without assistance other than the use of orthotics or braces
- Able to attend in person at the study clinic
Exclusion Criteria
- Any surgery on either leg
- Neurologic (nervous system) disease other than CMT
- Implanted metal or medical devices not safe for imaging
- Pregnancy
Will I be paid for my time?
Yes
IRB#: IRB_00195630
PI: Amy Lenz
Department: ORTHOPEDIC CLINIC
Approval Date: 2026-02-25 07:00:00
Study Categories: Bone and Muscle Studies, Brain Health Studies
Specialties: Neurology, Orthopaedic Surgery, Pediatric Neurology, Physical Medicine & Rehabilitation
I am Interested